박사님 감사합니다. 아래 논문에 의하면 약 5%정도의 파라퀘트만 흡수되고 나머지는 배설및 대사된다고 하는데,,..


Treatment of paraquat poisoning in man: methods to prevent absorption. Meredith TJ, Vale JA.Hum Toxicol. 1987 Jan;6(1):49-55.
Theoretically, absorption of an ingested dose of paraquat may be reduced by gastric lavage, induced emesis, whole-gut lavage or by the oral administration of absorbent substances.
Animal experiments suggest that paraquat is absorbed poorly from the stomach and absorbed incompletely (less than 5%) from the small intestine over a 1-6 h period.
Although gastric lavage would therefore seem a logical way to ameliorate the toxicity of an ingested dose of paraquat, peak plasma concentrations are attained rapidly and evidence for the efficacy of gastric lavage in man is poor.
Gut lavage has been shown to remove only a small proportion of an ingested dose of paraquat. At the flow rates employed in man (75 ml/min), approximately 0.5-1.0 litres of lavage fluid/h may be absorbed across the intestinal wall. Since there is a theoretical risk of increasing paraquat absorption, the use of whole-gut lavage cannot be recommended.
Bipyridilium herbicides are absorbed by soil and clay minerals, and montmorillonite in particular has been shown to be a strong binding agent in vitro. Accordingly, the use of Fuller\'s Earth (calcium montmorillonite) and Bentonite (sodium montmorillonite) for the treatment of poisoning has been investigated in animal models.(ABSTRACT TRUNCATED AT 250 WORDS)

물론 논문발표 내용이 다 맞는다고는 볼 수 없지만...위와 장관에 파라콰트가 5%이하로 poorly absortion된다고 하는데,
상기 논문은 동물실험을 대상으로 발표되었는데, 사람하고는 좀 다른 데이타가 나올 수 있는지 의문입니다..
저에게는 아주 큰 혼선으로 다가 옮니다..
이충호배상..
밤늦도록 논문검색을 하다보니까.. 벌써 새벽이 다가 오는 것 같습니다.